Metallic derivatives of dioxydiaminoarsenobenzene.



' preferably so as mannaivrsz, or sevens, rarer irmrarric DERIVATIVES or 'moxrmaivnnoansrnosen.'

ll ,269, "8%., The Drawing.

To all whomiit may: 6mm.-

lBe it known that ll, JEAN DANrsz, a citizen of the Republic of France, residing at Sevres, Seine-et-Oise, in the Republic of France, have invented certain new and "useful Improvements in Metalllc Derivatives of lDloxydiaminoarsenobenzene, of which the following is a Specification.

It is known that compounds may be obtained from dioxydiaminoarsenobenzene hydrochlorid and various mercury salts but it is diflicult to use these bodies especially therapeutically because they are but slightly sol-'- uble in acidulated water and decompose rapidlyon adding soda. 7

According to the presentinvention, bodies are obtained which are more soluble andmuch more stable in a feebly alkaline solution. This object is achievedby treating the known products with antimony compounds,

to yield antimonyl. compounds.

The products so obtained, have the great 5 therapeutic advantage that they are appreciably more activejand less toxic than the arsenobenzene compounds whichhavebeen subjected to experiment so far.

Example. I

' Mix 10 grams of ,dioxydiaminoarsenobenzene hydrochlorid (606) dissolved in 100 c. c. of methyl alcoholzas solvent with 4:

grams of antimony chlorid dissolved in 4: c. c. of methyl alcohol and 1 gram-of mercuri'c iodid dissolved in 90 c. c. of methyl aleohol. This gives a perfectly limpid cherryred liquid from which can be precipitated by ether a yellowish-red powder of varying depthofcolor. I

Specification of Letters Patent. Pafle-mtjredl slimmer; t, fifijlfihi Application filed Ju1 2ai91c. Serial No. 111,941. '1

" I Thislpowder has an acid reaction; it easily dissolves in water and ma slight excess of caustic soda.

The alkalinesolution of this powder in methyl alcohol can be" again precipitated by ether giving a sodium compound of dioxydiaminoarsenobenzene, mercuric iod id and antimonyl which is very easily soluble in waterlup to 10%)., v

- I declare that what I claim is 1. Process for the manufacture of a stable derivative of dioXydiaminoa-rsenobenzene by treating it with a mercury salt and an antimony salt: i i l 2. Process for the manufacture of a stable derivative of .dioxydiaminoarsenobenzene by treating it with a mercuric iodid and an antimony salt."

. 3. Process for the manufacture of a stable derivative of dioxydiaminoarsenobenzene by treating it with amercury salt and an antimonious chlorid,

4t. A stable derivative of dioydiaminoarsenobenzene containing mercury and antimonyl.

asan nanvsz.

Witness CHAs. P. Pnnssmz. 

